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Speed Buster (スピードバスター) is a fictional character in the 2007 video game No More Heroes. She is a 76-year-old assassin who lives in the abandoned Speed City and is the oldest ranked member of the United Assassins Association. Ranked third in the UAA, Speed Buster is a woman who claims men to be unbelievably stubborn and foolish. She has also recently become very hard of hearing or at least pretends to. She lacks the fighting skill of her own, but her powerful energy cannon-the Buster Launcher-more than makes up for her physical frailty.
She kills Thunder Ryu in a duel before Travis Touchdown's ranking match against her begins, causing the younger assassin to swear revenge. Unfortunately, his attempts to confirm Speed Buster's identity give her the time she needs to reset her energy cannon, forcing Travis to dodge into the many abandoned houses and alleys of the city to evade her blasts. After running out of hiding places, Travis knocks over a chain of telephone poles, with the last one damaging the Buster Launcher beyond operating capacity. With the old lady's main weapon offline, Travis easily covered the last few feet between him and the third-ranked assassin, slicing the Buster Launcher in half as he did so.
Speed Buster knew Thunder Ryu before they fought; despite her initial attitude, she claims to have thought of Thunder Ryu as a good man and believes Travis will develop into one as well. She gives Travis a quick kiss on the cheek before accepting her fate: a swift decapitation by beam katana.